おすすめの製品
由来生物
rabbit
品質水準
物質
colorless
クローン
0W9Z8, monoclonal
フォーム
liquid
分子量
45-53 kDa
化学種の反応性
human, rat, rat
濃度
0.5 mg/mL
テクニック
western blot: 1:500 - 1:2000
色
colorless
アイソタイプ
IgG
免疫原配列
METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVK
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... F3(2152)
詳細
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Coagulation factor III/Tissue Factor (P13726).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
アプリケーション
WB
保管分類コード
10 - Combustible liquids
WGK
WGK 1
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