SAB5702261

Anti-MCM2 Antibody, clone 0Q10S9, Rabbit Monoclonal

• 別名: MCM2,BM28,CCNL1,CDCL1,D3S3194,DFNA70,MITOTIN,cdc19
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 0Q10S9, monoclonal
• フォーム: liquid
• 分子量: 125 kDa
• 化学種の反応性: human, rat, rat
• 濃度: 0.38 mg/mL
• テクニック: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:100 - 1:200; western blot: 1:500 - 1:2000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDE
• UniProtアクセッション番号: P49736
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MCM2(4171)

詳細

詳細

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MCM2 (P49736).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

WB, IHC, IF/ICC

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1