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MCM2

minichromosome maintenance complex component 2

Synonyme:
BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(4171) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
  • Mouse(17216) minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
  • Rat(312538) minichromosome maintenance complex component 2
  • domestic guinea pig(100722936) minichromosome maintenance complex component 2
  • naked mole-rat(101710978) minichromosome maintenance complex component 2
  • sheep(101116097) minichromosome maintenance complex component 2
  • Zebrafish(192338) MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
  • domestic cat(101090176) minichromosome maintenance complex component 2
  • dog(484622) minichromosome maintenance complex component 2
  • cow(510120) minichromosome maintenance complex component 2
  • chicken(416027) minichromosome maintenance complex component 2
  • Thale Cress(841056) minichromosome maintenance protein 2
  • fruit fly(40973) Minichromosome maintenance 2

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified, ,
Speziesreaktivität
human, mouse
Anwendung
immunohistochemistry
western blot
Rabbit anti-MCM2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Speziesreaktivität
human, mouse
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-MCM2 antibody, Rabbit monoclonal, clone SP85, recombinant, expressed in proprietary host, affinity isolated antibody,
Speziesreaktivität
bovine, dog, frog, human, mouse, rat
Anwendung
flow cytometry
immunohistochemistry

western blot
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human MCM2,
Spezies
human
MISSION® esiRNA, targeting mouse Mcm2,
Spezies
mouse