SAB5702040

Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal

• 別名: ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 5C5N7, monoclonal
• フォーム: liquid
• 分子量: 58 kDa
• 交差性: human
• 濃度: 1.75 mg/mL
• テクニック: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKS
• UniProtアクセッション番号: P11511
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CYP19A1(1588)

詳細

詳細

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Aromatase (CYP19A1) (P11511).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

WB, IHC, IF/ICC

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1