SAB5701896

Anti-Phospho-Erk1/2-T202/Y204 antibody produced in rabbit

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: liquid
• 化学種の反応性: human, rat, mouse
• 濃度: 2.42 mg/mL
• テクニック: western blot: 1:500-1:2000
• UniProtアクセッション番号: P28482/P2736
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pThr202/pTyr204)

詳細

詳細

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

免疫原

A phospho specific peptide corresponding to residues surrounding T202/Y204+T185/Y187 of human ERK1+ERK2.

物理的形状

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable