SAB5700456

Anti-Phospho-PPP1CA-T320 antibody produced in rabbit

• 別名: PP-1A, PP1A, PP1alpha, PPP1A, PPP1CA
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: 32; 37; 38
• 化学種の反応性: mouse, human, rat
• 濃度: 2.36 mg/ml
• テクニック: immunohistochemistry: 1:50-1:100; western blot: 1:500-1:2000
• UniProtアクセッション番号: P62136
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pThr320)
• 遺伝子情報: human ... PPP1CA(5499)

詳細

詳細

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

免疫原

A phospho specific peptide corresponding to residues surrounding T320 of human PPP1CA

物理的形状

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保管および安定性

Store at -20℃. Avoid freeze / thaw cycles.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable