SAB5700452

Anti-Phospho-ACLY-S455 antibody produced in rabbit

• 別名: ACL, ACLY, ATPCL, CLATP
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: 119; 120; 91
• 化学種の反応性: rat, mouse, human
• 濃度: 1.15 mg/ml
• テクニック: immunohistochemistry: 1:50-1:100; immunoprecipitation (IP): 1:50-1:100; western blot: 1:500-1:2000
• UniProtアクセッション番号: P53396
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer455)
• 遺伝子情報: human ... ACLY(47)

詳細

詳細

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

免疫原

A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2).

物理的形状

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保管および安定性

Store at -20℃. Avoid freeze / thaw cycles.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable