SAB5700048

Anti-SIRT1 antibody produced in rabbit

• 別名: SIR2, SIR2L1, SIR2alpha, SIRT1, sirtuin 1
• UNSPSCコード: 12352203
• NACRES: NA.43

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: 61; 81
• 化学種の反応性: mouse, rat, human
• 濃度: 1.70 mg/ml
• テクニック: immunofluorescence: 1:50-1:200; immunohistochemistry: 1:50-1:200; immunoprecipitation (IP): 1:50-1:100; western blot: 1:500-1:2000
• UniProtアクセッション番号: Q96EB6
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SIRT1(23411)

詳細

詳細

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 448-747 of human SIRT1 (NP_036370.2).

物理的形状

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保管および安定性

Store at -20℃. Avoid freeze / thaw cycles.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable