SAB5300151

Monoclonal Anti-AIFM1 antibody produced in mouse

clone 4E7, ascites fluid

• 別名: AIF, AIFM1, COXPD6, MGC111425, PDCD8
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: ascites fluid
• 抗体製品タイプ: primary antibodies
• クローン: 4E7, monoclonal
• 分子量: 67 kDa
• 交差性: mouse, monkey, human, rat
• テクニック: direct ELISA: 1:10,000; flow cytometry: 1:200-1:400; immunohistochemistry: 1:200-1:1,000; indirect immunofluorescence: 1:200-1:1,000; western blot: 1:500-1:2,000
• アイソタイプ: IgG2b
• NCBIアクセッション番号: NM_001130846
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... AIF(9131)

詳細

詳細

AIFM1 (apoptosis inducing factor mitochondria associated 1) codes for apoptosis-inducing factor 1(AIF). It is located on human chromosome Xq26.1. AIF is a caspase-independent cell death effector.

免疫原

Purified recombinant fragment of human AIF expressed in E.coli.
Mouse monoclonal antibody raised against AIF

生物化学的／生理学的作用

AIFM1 (apoptosis inducing factor mitochondria associated 1) possesses redox activity, which helps in oxidative phosphorylation. In the mitochondria, AIFM1 helps in assembling or maintaining the mitochondrial respiratory complexes I and III. It plays a vital role in apoptosis. This gene is associated with COXPD6 (combined oxidative phosphorylation deficiency, encephalomyopathy, Cowchock syndrome and X-linked deafness with neuropathy.

物理的形状

Ascitic fluid containing 0.03% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable