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Key Documents

SAB4503583

Sigma-Aldrich

Anti-CD4 antibody produced in rabbit

affinity isolated antibody

別名:

CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 precursor

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

形状

buffered aqueous solution

分子量

antigen 51 kDa

化学種の反応性

human, mouse

濃度

~1 mg/mL

テクニック

ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... CD4(920)

関連するカテゴリー

詳細

Anti-CD4 Antibody detects endogenous levels of total CD4 protein.
CD4 (CD4 molecule) is present in the surface of specific leukocytes. CD4 contains four ecto-domains (D1-D4) of which D1, D2, and D4 contain disulfide bonds. It is mapped to human chromosome 12p13.31.

免疫原

The antiserum was produced against synthesized peptide derived from human CD4.

Immunogen Range: 401-450

アプリケーション

Anti-CD4, C-Terminal antibody has been used in immunohistochemical staining.

生物化学的/生理学的作用

CD4 (CD4 molecule) helps in the activation of immunostimulatory T-cells. It serve as a primary receptor for HIV-1 entry.This molecule plays an important role on cell membrane mechanical characteristics and can be used in the development of cell biology and medicine.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation
Ashraf MI, et al.
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(3), 808-820 (2016)
M I Ashraf et al.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(3), 808-820 (2015-11-26)
Lipocalin 2 (Lcn2) is rapidly produced by damaged nephron epithelia and is one of the most promising new markers of renal injury, delayed graft function and acute allograft rejection (AR); however, the functional importance of Lcn2 in renal transplantation is
The role of CD4 on mechanical properties of live cell membrane
Bui VC and Nguyen TH
Journal of Biomedical Materials Research Part A, 104(1), 239-244 (2016)
Isochromosomes 12p and 9p: parental origin and possible mechanisms of formation
Dutly F, et al.
European Journal of Human Genetics, 6(2), 140-144 (1998)
Human CD4 Metastability Is a Function of the Allosteric Disulfide Bond in Domain 2
Owen GR, et al.
Biochemistry, 55(15), 2227-2237 (2016)

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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