おすすめの製品
由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen 16 kDa
交差性
human, rat, mouse
濃度
~1 mg/mL
テクニック
ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... CALM1(801)
詳細
Anti-Calmodulin Antibody detects endogenous levels of total Calmodulin protein.
Calmodulin (CaM), a highly conserved Ca2+-binding protein, is mapped to human chromosome 14q32. Calmodulin is a small protein abundantly present in the brain and coded by three genes (CALM1-3).
Calmodulin (CaM), a highly conserved Ca2+-binding protein, is mapped to human chromosome 14q32. Calmodulin is a small protein abundantly present in the brain and coded by three genes (CALM1-3).
免疫原
The antiserum was produced against synthesized peptide derived from human Calmodulin.
Immunogen Range: 46-95
Immunogen Range: 46-95
アプリケーション
Anti-Calmodulin antibody has been used in western blotting.
生物化学的/生理学的作用
Calmodulin (CaM) possesses Ca2+-dependent modulatory roles. It participates in cell proliferation and muscle activity. Calmodulin plays a major role in catecholaminergic polymorphic ventricular tachycardia (CPVT) and in long QT syndrome (LQTS). This protein modulates the transcriptional processes required for proper heart function.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SAB4503194-100UG:
最新バージョンのいずれかを選択してください:
The Arrhythmogenic Calmodulin Mutation D129G Dysregulates Cell Growth, Calmodulin-dependent Kinase II Activity and Cardiac Function in Zebrafish.
Berchtold MW, et al.
The Journal of Biological Chemistry, 291(52), 26636?26646-26636?26646 (2016)
Paeoniflorin, the Main Active Ingredient of Shuyu Capsule, Inhibits Cav1. 2 and Regulates Calmodulin/Calmodulin-Dependent Protein Kinase II Signalling.
Song C, et al.
BioMed Research International, 2017 (2017)
Orthologs of seven genes (AKT1, CDC42BPB, DIO3, EIF5, JAG2, KLC, NDUFB1) from human chromosome 14q32 map to distal chicken chromosome 5.
Boyd Y, et al.
Mammalian Genome, 13(2), 120-122 (2002)
Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Rocchetti M, et al.
Cardiovascular Research, 113(5), 531-541 (2017)
Presynaptic Calmodulin targets: lessons from structural proteomics.
Lipstein N, et al.
Expert Review of Proteomics, 14(3), 223-242 (2017)
Global Trade Item Number
カタログ番号 | GTIN |
---|---|
SAB4503194-100UG | 4061837746024 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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