おすすめの製品
由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen 126 kDa
交差性
human
濃度
~1 mg/mL
テクニック
ELISA: 1:1000
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... TERT(7015)
詳細
Anti-Telomerase Antibody detects endogenous levels of total Telomerase protein.
The TERT (telomerase reverse transcriptase) gene is mapped to human chromosome 5p15.33 and encodes for a ribonucleoprotein.
免疫原
The antiserum was produced against synthesized peptide derived from human Telomerase.
Immunogen Range: 796-845
Immunogen Range: 796-845
生物化学的／生理学的作用
TERT (telomerase reverse transcriptase) catalyzes the de novo synthesis of telomere and results in cellular immortalization to maintain chromosomal stability. Mutations in TERT causes different types of malignancies such as gliomas, gastric cancer, and anaplastic thyroid cancer. Therefore, TERT serves as an early prognostic biomarker.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
最新バージョンのいずれかを選択してください：
Silencing of hTERT blocks growth and migration of anaplastic thyroid cancer cells.
Maggisano V
Molecular and Cellular Endocrinology, 448, 34-40 (2017)
The role of TERT-CLPTM1L SNPs, hTERT expression and telomere length in the pathogenesis of oral squamous cell carcinoma.
Carkic J
Journal of Oral Science, 58(4), 449-458 (2016)
Brain regions associated with telomerase reverse transcriptase promoter mutations in primary glioblastomas.
Fan X
Journal of Neuro-Oncology, 28(3), 455-462 (2016)
Lung cancer susceptibility locus at 5p15.33.
McKay JD
Nature Genetics, 40(12), 1404-1406 (2008)
Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expression.
Tang B
Oncotarget, 7(10), 11364-11379 (2016)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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