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Key Documents

SAB4501470

Sigma-Aldrich

Anti-5-HT-1B antibody produced in rabbit

affinity isolated antibody

別名:

5-HT-1B, 5-HT-1D-β, 5-HT1B, 5-hydroxytryptamine receptor 1B, Serotonin receptor 1B

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

形状

buffered aqueous solution

分子量

antigen 43 kDa

化学種の反応性

human, mouse, rat

濃度

~1 mg/mL

テクニック

ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... HTR1B(3351)

関連するカテゴリー

詳細

5-HT-1B/HTR1B (5-hydroxytryptamine receptor 1B) is a presynaptic and postsynaptic receptor, present in the basal ganglia, hippocampus and cortex. It is located on human chromosome 6q14.1.
Anti-5-HT-1B Antibody detects endogenous levels of total 5-HT-1B protein.

免疫原

The antiserum was produced against synthesized peptide derived from human 5-HT-1B.

Immunogen Range: 201-250

生物化学的/生理学的作用

5-HT-1B/HTR1B (5-hydroxytryptamine receptor 1B) plays an important role in locomotion, feeding and thermoregulation and also in arterial contractile regulation mechanisms. It participates in regulating the effects of serotonin.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Polymorphisms in the 5′-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression.
Duan J, et al.
Molecular Psychiatry, 8(11), 901-910 (2003)
Katsura Nozawa et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(9), 3408-3413 (2009-02-13)
Serotonin (5-hydroxytryptamine; 5-HT) is abundantly present throughout the gastrointestinal tract and stored mostly in enterochromaffin (EC) cells, which are located on the mucosal surface. 5-HT released from EC cells stimulate both intrinsic and extrinsic nerves, which results in various physiological
Nadja Osterberg et al.
Cell and tissue research, 336(1), 11-20 (2009-02-19)
Serotonergic (5-HT) neurons of the reticular formation play a key role in the modulation of behavior, and their dysfunction is associated with severe neurological and psychiatric disorders, such as depression and schizophrenia. However, the molecular mechanisms underlying the differentiation of

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