おすすめの製品
由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen 23 kDa
交差性
human
濃度
~1 mg/mL
テクニック
ELISA: 1:10000
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... APOBEC3A(200315)
関連するカテゴリー
詳細
APOBEC3A (apolipoprotein B mRNA editing enzyme catalytic subunit 3A) belongs to the AID/APOBEC family of enzymes. It is located on human chromosome 22q13.1.
Anti-APOBEC3A antibody detects endogenous levels of total APOBEC3A protein.
免疫原
The antiserum was produced against synthesized peptide derived from human APOBEC3A.
Immunogen Range: 27-76
Immunogen Range: 27-76
アプリケーション
Anti-APOBEC3A antibody has been used in western blotting.
生物化学的/生理学的作用
APOBEC3A (apolipoprotein B mRNA editing enzyme catalytic subunit 3A) deaminates methylated cytosine bases in DNA. It is considered as a viral DNA mutator and performs broad antiviral activity.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
最新バージョンのいずれかを選択してください:
Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A
Aynaud MM, et al.
The Journal of Biological Chemistry (2012)
Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage
Suspene R, et al.
Nucleic Acids Research, 45(6), 3231-3241 (2017)
Heat Increases the Editing Efficiency of Human Papillomavirus E2 Gene by Inducing Upregulation of APOBEC3A and 3G
Yang Y, et al.
The Journal of Investigative Dermatology, 137(4), 810-818 (2017)
APOBEC3A efficiently deaminates methylated, but not TET-oxidized, cytosine bases in DNA
Schutsky EK, et al.
Nucleic Acids Research, 45(13), 7655-7665 (2017)
Jan-Hendrik Bockmann et al.
The Journal of infectious diseases, 220(4), 567-577 (2019-03-30)
Type III interferons (IFNs) (λ1-3) activate similar signaling cascades as type I IFNs (α and β) via different receptors. Since IFN-α and lymphotoxin-β activate cytosine deamination and subsequent purging of nuclear hepatitis B virus (HBV) DNA, we investigated whether IFN-β
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