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Merck

SAB4500465

Sigma-Aldrich

Anti-CRHR1 antibody produced in rabbit

affinity isolated antibody

別名:

CRF-R, CRF1, CRH-R 1, Corticotropin-releasing factor receptor 1, Corticotropin-releasing hormone receptor 1

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

フォーム

buffered aqueous solution

分子量

antigen 50 kDa

化学種の反応性

rat, mouse, human

濃度

~1 mg/mL

テクニック

ELISA: 1:5000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... CRHR1(1394)

詳細

Anti-CRHR1 Antibody detects endogenous levels of total CRHR1 protein.
CRHR1 (corticotropin releasing factor receptor 1) is a member of the G-protein-coupled receptor superfamily of brain-gut neuropeptides. It is highly expressed in the amygdala, hippocampus and frontal cortex. It has 13 exons and located on human chromosome 17q12-q22.

免疫原

The antiserum was produced against synthesized peptide derived from human CRHR1.

Immunogen Range: 75-124

アプリケーション

Anti-CRHR1 antibody has been used in immunoprecipitation and western blotting.

生物化学的/生理学的作用

CRHR1 (corticotropin releasing factor receptor 1) blocks the multiplication of endocrine-related cancer cell lines. It helps to initiate signal transduction pathways, that controls various functions like stress, reproduction, immune response and obesity.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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以前この製品を購入いただいたことがある場合

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文書ライブラリにアクセスする

Urocortinergic system in the testes of normal and cryptorchid dogs
Squillacioti C, et al.
Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft, 207, 91-96 (2016)
Family Economic Hardship, Corticotropin-Releasing Hormone Receptor Polymorphisms, and Depressive Symptoms in Rural African-American Youths
Chen YF and Brody GH
The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine, 57(2), 235-240 (2015)
Association analysis of polymorphisms of the CRHR1 gene with infantile spasms
Yang G, et al.
Molecular Medicine Reports, 12(2), 2539-2546 (2015)
Qiang-Song Wang et al.
Food & function, 12(5), 2211-2224 (2021-02-18)
As a functional bowel disorder, irritable bowel syndrome (IBS), especially IBS-diarrhea (IBS-D), affects approximately 9-20% of the population worldwide. Classical treatments for IBS usually result in some side effects and intestinal microbial disorders, which inhibit the clinical effects. Natural edible
Urocortin protects chondrocytes from NO-induced apoptosis: a future therapy for osteoarthritis?
Intekhab-Alam NY, et al.
Cell Death & Disease (2013)

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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