SAB4300438

Anti-ZAP70 (Ab-493) antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-FLJ17670 antibody produced in rabbit, Anti-FLJ17679 antibody produced in rabbit, Anti-SRK antibody produced in rabbit, Anti-STD antibody produced in rabbit, Anti-zeta-chain (TCR) associated protein kinase 70kDa antibody produced in rabbit
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: ~70 kDa
• 化学種の反応性: rat, mouse, human
• 濃度: 1 mg/mL
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• アイソタイプ: IgG
• 免疫原配列: (S-Y-Y-T-A)
• NCBIアクセッション番号: NP_001070.2
• UniProtアクセッション番号: P43403
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ZAP70(7535)

詳細

免疫原

Peptide sequence around aa. 491-495 (S-Y-Y-T-A), according to the protein ZAP70.

特徴および利点

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ターゲットの説明

ZAP70 is a 70-kD tyrosine phosphoprotein that associates with the zeta chain and undergoes tyrosine phosphorylation following TCR stimulation. The ZAP70 gene is expressed in T- and natural KILLER cells. Protein-Tyrosine Kinases (PTKs) play an integral role in T-cell activation. Stimulation of the T-cell antigen receptor results in tyrosine phosphorylation of a number of cellular substrates. One of these is the TCR-zeta chain, which can mediate the transduction of extracellular stimuli into cellular effector functions.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable