SAB4300028

Anti-phospho-MEF2A (pThr³¹²) antibody produced in rabbit

affinity isolated antibody

• 別名: 抗ADCAD1抗体 ウサギ宿主抗体, 抗RSRFC4抗体 ウサギ宿主抗体, 抗RSRFC9抗体 ウサギ宿主抗体
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: ~54 kDa
• 交差性: human, rat, mouse
• 濃度: 1 mg/mL
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200
• アイソタイプ: IgG
• 免疫原配列: (L-A-TP-P-V)
• NCBIアクセッション番号: NP_001124398.1
• UniProtアクセッション番号: Q02078
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pThr312)
• 遺伝子情報: human ... MEF2A(4205)

詳細

免疫原

Peptide sequence around phosphorylation site of threonine 312 (L-A-T(p)-P-V), according to the protein MEF2A.

特徴および利点

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ターゲットの説明

The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable