SAB4200298

Anti-Tensin 1 (internal) antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody

• 別名: Anti-TNS, Anti-TNS1
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: WB
• クローン: polyclonal
• 化学種の反応性: human, rat
• citations: 3
• テクニック: western blot: 1-2 μg/mL using HEK-293T cells overexpressing human tensin1.; western blot: 1.5-3 μg/mL using lysates of A10 cells

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 225 kDa (rat); antigen ~150 kDa (human)
• 化学種の反応性: human, rat
• 強化検証: recombinant expression; Learn more about Antibody Enhanced Validation
• 濃度: ~1.5 mg/mL
• テクニック: western blot: 1-2 μg/mL using HEK-293T cells overexpressing human tensin1.; western blot: 1.5-3 μg/mL using lysates of A10 cells
• UniProtアクセッション番号: Q9HBL0
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... TNS1(7145) ; mouse ... Tns1(21961) ; rat ... Tns1(301509)

詳細

詳細

Tensin 1, also known as TNS1, is a member of tensin protein family. Tensins are multi domain proteins containing homologous C1, protein phosphatases (PTPases), C2, Src homology 2 (SH2) domains and pTyr-binding (PTB) domains. Tensin 1 mRNA is widely expressed in mouse embryo and various human adult tissues and is localized to focal adhesions.

免疫原

synthetic peptide corresponding to a sequence located in the internal region of human tensin1, conjugated to KLH. The corresponding sequence is identical in rat and mouse tensin1.

アプリケーション

Anti-Tensin 1 (internal) antibody produced in rabbit has been used in immunoblotting.

生物化学的／生理学的作用

Tensins play an important role in regulating cell shape and motility. Tensin 1 is involved in organizing the actin cytoskeleton and mediating signal transduction. TNS1 is implicated in myofibroblast differentiation. In addition, it also helps myofibroblasts to form nascent fibronectin and collagen matrix.

物理的形状

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable