SAB4200197

モノクロナール抗ペリオスチン マウス宿主抗体

clone 47, purified from hybridoma cell culture

• 別名: 抗OSF2抗体, 抗PDLPOSTN抗体, 抗POSTN抗体
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: 47, monoclonal
• フォーム: buffered aqueous solution
• 分子量: antigen ~88 kDa
• 交差性: human
• 濃度: ~1.0 mg/mL
• テクニック: western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin
• アイソタイプ: IgG1
• UniProtアクセッション番号: Q15063
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... POSTN(10631)

詳細

詳細

Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3.

免疫原

human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein.

アプリケーション

Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe.

生物化学的／生理学的作用

Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable