SAB3701180

Anti-Mouse IgG2a (γ-chain specific)-Biotin antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 結合体: biotin conjugate
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: secondary antibodies
• クローン: polyclonal
• 形状: lyophilized powder
• 化学種の反応性: mouse
• テクニック: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• 輸送温度: wet ice
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Immunoglobulin G (IgG) consists of a γ heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. It belongs to the immunoglobulin family and is a widely expressed serum antibody. Disulfide bonds link the two heavy chains, the heavy and light chains and also links residues inside the chains. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. IgG2 is involved in immune responses to bacterial capsular polysaccharide antigens. Its deficiency has been linked to an increased susceptibility to bacterial infections.

特異性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse antigens coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Biotin, Anti-Rabbit Serum, Mouse IgG and Mouse Serum. Specificity was confirmed by ELISA. Typically less than 1% cross reactivity was observed against other Mouse heavy chain isotypes.

免疫原

Mouse IgG2a heavy chain

物性

抗体フォーマット：IgG

物理的形状

0.02 M リン酸カリウム、0.15 M 塩化ナトリウム、pH 7.2、10 mg/mL ウシ血清アルブミン（BSA）-免疫グロブリン含有（プロテアーゼフリー）

再構成

Reconstitute with 1.0 mL deionized water (or equivalent).

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS06,GHS09
• シグナルワード: Danger
• 危険有害性情報: H302,H311,H411
• 注意書き: P280 - P301 + P312 + P330 - P302 + P352 + P312
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2
• 補足的ハザード: EUH032
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable