SAB3500117

Anti-OCIAD1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-OCIA domain-containing protein 1, Anti-Ovarian cancer immuno-reactive antigen domain-containing protein 1
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 化学種の反応性: human
• テクニック: immunofluorescence: suitable; indirect ELISA: suitable; western blot: suitable
• NCBIアクセッション番号: NP_060300
• UniProtアクセッション番号: Q9NX40
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... OCIAD1(54940)

詳細

免疫原

OCIAD1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human OCIAD1.

特徴および利点

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ターゲットの説明

OCIAD1 was identified via immunoscreening of an ovarian carcinoma cDNA library from ovarian cancer patients and is expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland. Two isoforms of OCIAD1 are known to exist; the shorter isoform is restricted to the central nervous system. OCIAD1 is a transmembrane protein whose overexpression in HEY ovarian cancer cells increased lysophosphatidic acid- (LPA-)induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin10/11. This adhesion is not blocked by LY294002 and GF109203X, suggesting that OCIAD1 does not use protein kinase C and PI3 kinase signaling pathways to exert its effect on adhesion.

関連事項

The action of this antibody can be blocked using blocking peptide SBP3500117.

物理的形状

約1 mg/mLのPBS (0.02％ アジ化ナトリウム含有)

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable