SAB2702341

Monoclonal Anti-ARID1A antibody produced in mouse

clone GT3611, affinity isolated antibody

• 別名: B120, BAF250, BAF250a, BM029
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: GT3611, monoclonal
• フォーム: buffered aqueous solution
• 分子量: 242kDa
• 交差性: human, mouse
• 濃度: 2.61mg/mL
• テクニック: immunofluorescence: 1:100-1:1,000; immunohistochemistry: 1:100-1:1,000; western blot: 1:500-1:3,000
• アイソタイプ: IgG2b
• UniProtアクセッション番号: O14497
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... ARID1A(8289)

詳細

免疫原

Recombinant protein encompassing a sequence within the C-terminus region of human ARID1A.

アプリケーション

Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生物化学的／生理学的作用

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

その他情報

Purification: Affinity purified by Protein G

物理的形状

Phosphate-buffered saline, no preservative added.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable