おすすめの製品
由来生物
mouse
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
GT1315, monoclonal
形状
buffered aqueous solution
分子量
189kDa
化学種の反応性
human
濃度
1mg/mL
テクニック
western blot: 1:500-1:3000
アイソタイプ
IgG1
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... CEP152(22995)
詳細
CEP152 (centrosomal protein 152), a mammalian ortholog of Drosphila asterless is a component of mammalian centrosomes. It is located on human chromosome 15.
免疫原
Recombinant protein encompassing a sequence within the N-terminus region of human CEP152.
アプリケーション
Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
生物化学的/生理学的作用
This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq]
CEP152 (centrosomal protein 152) plays an important role in cell division and development. It is highly essential for the recruitment of centriole of Plk4 (polo-like kinase 4) and centriole duplication at the time of cell cycle.
CEP152 (centrosomal protein 152) plays an important role in cell division and development. It is highly essential for the recruitment of centriole of Plk4 (polo-like kinase 4) and centriole duplication at the time of cell cycle.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
その他情報
Purification: Affinity purified by Protein G
物理的形状
Phosphate-buffered saline, no preservative added.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication.
Journal of Cell Science, 126(14), 3223-3233 (2013)
Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15.
American Journal of Human Genetics, 65(5), 1465?1469-1465?1469 (1999)
Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4.
American Journal of Human Genetics, 87(1), 40-51 (2010)
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