SAB1300893
Anti-TYRO10 antibody produced in rabbit
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
別名:
Anti-Discoidin domain receptor 2, Anti-Neurotrophic tyrosine kinase, Anti-Receptor protein-tyrosine kinase TKT, Anti-Tyrosine-protein kinase TYRO 10, receptor-related 3
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About This Item
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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
saturated ammonium sulfate (SAS) precipitated
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
化学種の反応性
human
テクニック
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... TYRO10(4921)
詳細
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain, not previously described for RTKs.
免疫原
TYRO10 ()
This antibody is generated from rabbits immunized with a his tag recombinant protein of human TYRO10.
This antibody is generated from rabbits immunized with a his tag recombinant protein of human TYRO10.
物理的形状
精製済みポリクローナル抗体のPBS溶液(0.09%(W/V)アジ化ナトリウム含有)
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, 23(6), 335-343 (2014-07-26)
Tissue inhibitor of metalloproteinase-2 (TIMP-2) is an endogenous inhibitor of matrix metalloproteinases (MMPs) that attenuates maladaptive cardiac remodeling in ischemic heart failure. We examined the effects of TIMP-2 on human cardiac fibroblast activation and extracellular matrix (ECM) remodeling. Human cardiac
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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