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Merck

SAB1103857

Sigma-Aldrich

Anti-MUSTN1 (6-20) antibody produced in rabbit

IgG fraction of antiserum

別名:

Anti-Musculoskeletal, embryonic nuclear protein 1, Anti-Mustang

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

結合体

unconjugated

抗体製品の状態

IgG fraction of antiserum

抗体製品タイプ

primary antibodies

クローン

polyclonal

フォーム

buffered aqueous solution

分子量

antigen ~9 kDa

化学種の反応性

human

テクニック

western blot: 1:500-1:2,000

UniProtアクセッション番号

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... MUSTN1(389125)

詳細

MUSTN1 gene was initially discovered in fracture callus tissue. The gene codes for a small nuclear protein and is known to be widely expressed in skeletal muscle. MUSTN1 expression is observed during embryogenesis in the developing muscles and somites. Its maximum expression is observed from the third month of life. The gene is highly conserved among the vertebrates. The gene is known to contain a nuclear localization sequence, phosphorylation and myristoylation sites.
Musculoskeletal, embryonic nuclear protein 1 (MUSTN1) is encoded by the gene is mapped to human chromosome 3p21.1.

免疫原

synthetic peptide corresponding to amino acids 6-20of human MUSTN1

生物化学的/生理学的作用

MUSTN1 is involved in bone development and regeneration, as well as chondrogenesis. It is critical in the regulation of myogenic differentiation and myofusion as its knock-down inhibits the processes.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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Lot/Batch Number

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文書ライブラリにアクセスする

Robert P Gersch et al.
Bone, 45(2), 330-338 (2009-05-05)
Mustn1 encodes a small nuclear protein expressed specifically in the musculoskeletal system that was originally identified as a strongly up-regulated gene during bone regeneration, especially in fracture callus proliferating chondrocytes. Further experiments were undertaken to investigate its expression and role
Cheng Liu et al.
American journal of physiology. Cell physiology, 298(5), C1100-C1108 (2010-02-05)
Mustn1 (Mustang, musculoskeletal temporally activated novel gene) was originally identified in fracture callus tissue, but its greatest expression is detected in skeletal muscle. Thus, we conducted experiments to investigate the expression and function of Mustn1 during myogenesis. Temporally, quantitative real-time
Allelic expression analysis of the osteoarthritis susceptibility locus that maps to chromosome 3p21 reveals cis-acting eQTLs at GNL3 and SPCS1
Gee F, et al.
BMC Medical Genetics, 15(1), 53-53 (2014)

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