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品質水準
アッセイ
≥98% (HPLC)
フォーム
solid
薬剤管理
USDEA Schedule IV
保管条件
desiccated
色
white
溶解性
DMSO: >30 mg/mL
H2O: insoluble
オーガナイザー
Abbott
保管温度
room temp
SMILES記法
O.Cl.CC(C)CC(N(C)C)C1(CCC1)c2ccc(Cl)cc2
InChI
1S/C17H26ClN.ClH.H2O/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;;/h6-9,13,16H,5,10-12H2,1-4H3;1H;1H2
InChI Key
KFNNPQDSPLWLCX-UHFFFAOYSA-N
遺伝子情報
human ... SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)
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アプリケーション
Sibutramine hydrochloride monohydrate was used as standard to screen dietary supplements for sibutramine using ion mobility spectrometer.1
生物化学的/生理学的作用
シブトラミンはセロトニン・ノルアドレナリン再取り込み阻害剤(SNRI)です。カロリー摂取を低下させ、エネルギー消費を亢進する抗肥満薬です。シブトラミンはマウス脳においてMPTP誘導性のドーパミン枯渇に拮抗します。
特徴および利点
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
S9944-BULK:
S9944-SMPL:
S9944-25MG:
S9944-50MG:
S9944-VAR:
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Journal of pharmaceutical and biomedical analysis, 54(3), 469-474 (2010-10-14)
In response to recent incidents of undeclared sibutramine, an appetite suppressant found in dietary supplements, we developed a method to detect sibutramine using hand-held ion mobility spectrometers with an analysis time of 15 s. Ion mobility spectrometry is a high-throughput
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Chromatograms
application for HPLCapplication for HPLCライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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