R3654

Anti-RbAp48 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-Retinoblastoma-binding protein
• MDL番号: MFCD02686588
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 48 kDa
• 化学種の反応性: human
• テクニック: indirect immunofluorescence: 1-2 μg/mL using HeLa cells fixed with paraformaldehyde-Triton; western blot: 0.5-1 μg/mL using MCF7 nuclear extracts
• UniProtアクセッション番号: Q09028
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... RBBP4(5928) ; mouse ... Rbbp4(19646) ; rat ... Rbbp4(313048)

詳細

詳細

Histone binding protein (RbAp48, also known as also known as RBBP4 or NURF55) contains 425 amino acids, tryptophan-aspartic acid (WD)-domain containing protein isolated as a retinoblastoma binding protein (RB1).

免疫原

synthetic peptide corresponding to amino acids 1-14 of human RbAp48, conjugated to KLH via a C-terminal added cysteine residue. The immunizing peptide is conserved in human, mouse, and rat.

アプリケーション

Anti-RbAp48 antibody produced in rabbit has been used in immunoprecipitation and western blot analysis. It may also be used in immunofluorescence.

生物化学的／生理学的作用

RbAp48 is found in association with chromatin remodeling complexes Sin3A/histone deacetylase (HDAC) and NURD (nucleosomal remodeling and deacetylation complex).

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)