PRS1112

抗CCR5抗体 ウサギ宿主抗体

IgG fraction of antiserum, buffered aqueous solution

• 別名: 抗ケモカイン(C-Cモチーフ)レセプター5抗体
• MDL番号: MFCD01864608
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: IgG fraction of antiserum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: predicted mol wt 39 kDa
• 化学種の反応性: human
• テクニック: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProtアクセッション番号: P51681
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CCR5(1234)

詳細

詳細

C-C motif chemokine receptor 5 (CCR5) is expressed by T lymphocytes, macrophages and monocytes. It belongs to the chemokine receptor family. The gene encoding this protein is localized on human chromosome 3p21.31.

免疫原

a peptide corresponding to amino acids 6-20 of human CCR5.

生物化学的／生理学的作用

C-C motif chemokine receptor 5 (CCR5) is a receptor for chemokine ligands-3, -4 and -5. It acts as a co-receptor for human immunodeficiency virus (HIV) entry in cells.The protein also has a role in leukocyte chemotaxis. CCR5 indirectly influence the aggregation of immune cells at the site of viral infection on mucosal surfaces. It also modulates activation of immune cells during inflammation.

関連事項

The action of this antibody can be blocked using blocking peptide SBP1112.

物理的形状

PBS溶液(0.02%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable