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免疫原
The epitope recognized by PLA0097 maps to a region between residues 975 and 1025 of human CREB Binding Protein using the numbering given in entry NP_004371.1 (GeneID 1387).
物理的形状
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide
その他情報
CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis.
免責事項
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保管分類コード
12 - Non Combustible Liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
PLA0097-100UL-KC:
PLA0097-100UL:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Yanmei Cui et al.
Oncogene, 38(27), 5516-5529 (2019-04-03)
The early recurrence of hepatocellular carcinoma (HCC) is the main obstacle for long-term survival of patients. Wnt/β-catenin signaling has been involved in the development and progression of HCC. However, the molecular changes that link Wnt/β-catenin activation and HCC early recurrence
Yujie Liu et al.
Molecular and cellular biology, 34(21), 3993-4007 (2014-08-27)
T-regulatory (Treg) cells are important to immune homeostasis, and Treg cell deficiency or dysfunction leads to autoimmune disease. A histone/protein acetyltransferase (HAT), p300, was recently found to be important for Treg function and stability, but further insights into the mechanisms
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