P300-05

Porcine Coronary Artery Endothelial: PCAEC (Cryovial)

• UNSPSCコード: 41106514
• NACRES: NA.81

特性

• 由来生物: Porcine coronary artery
• 品質水準: 100
• 形状: solid
• 包装: pkg of 500,000 cells
• メーカー／製品名: Cell Applications, Inc
• 成長モード: Adherent
• 核型: 2n = 38
• 形態: Endothelial
• テクニック: cell culture | mammalian: suitable
• 関連疾患: cardiovascular diseases
• 輸送温度: dry ice
• 保管温度: −196°C

詳細

詳細

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.


Arterial endothelial cells play critical roles in cardiac homeostasis, and insults to the endothelial cells have been linked to a variety of vascular diseases. Porcine artery endothelial cells provide a useful tool to study artery endothelial function and metabolism.PCAEC from Cell Applications, Inc. have been used to investigate a new mechanism of obesity-associated vascular disease by demonstrating that resistin, an adipocyte-derived cytokine implemented in insulin resistance and diabetes, can cause endothelial dysfunction in coronary arteries through oxidative stress and down-regulation of NO synthase (Kougias, 2005). Conversely, secretoneurin was shown to activate expression of NO synthase and calmodulin, leading to endothelial relaxation (Chan, 2011). PCAEC were also used in adhesion and transmigration experiments in a study investigating anti-inflammatory, cardioprotective effects of a novel adenosine-lidocaine drug formulation (Shi, 2012).

細胞株の由来

Artery

アプリケーション

cardiovascular function, angiogenesis, vascular biology, regulation of coronary blood flow, cardiac functions, effects of vaso-dilators, coagulation, fibrinolysis, vessel wall tone, cytokine production

構成

Porcine Endothelial Cell Growth Medium that contains 10% FBS and 10% DMSO

調製ノート

• 2nd passage, >500,000 cells in Porcine Endothelial Cell Growth Medium that contains 10% FBS and 10% DMSO
• Can be cultured at least 12 doublings

継代と培養方法

Please refer to the PCAEC Culture Protocol.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable