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About This Item
実験式（ヒル表記法）:
C12H11N3O2
CAS番号:
分子量:
229.23
MDL番号:
UNSPSCコード:
41106305
PubChem Substance ID:
NACRES:
NA.77
おすすめの製品
アッセイ
≥98% (HPLC)
形状
powder
色
off-white to light brown
溶解性
DMSO: ≥30 mg/mL
保管温度
2-8°C
SMILES記法
Nc1ncc2C(=O)CC(Cc2n1)c3ccco3
InChI
1S/C12H11N3O2/c13-12-14-6-8-9(15-12)4-7(5-10(8)16)11-2-1-3-17-11/h1-3,6-7H,4-5H2,(H2,13,14,15)
InChI Key
SOJUSNIBPPMLCC-UHFFFAOYSA-N
生物化学的／生理学的作用
NKY80 is a selective adenylyl cyclase-V inhibitor with greater than 200-fold selectivity for type V over the type II isoform.
特徴および利点
This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
N2165-5MG:
N2165-VAR:
N2165-25MG:
N2165-BULK:
試験成績書（COA）
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Cholangiocytes, the epithelial cells lining the biliary tree in the liver, express primary cilia that can detect several kinds of environmental signals and then transmit this information into the cell. We have reported that cilia are significantly reduced in cholangiocarcinoma
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