M7648

抗ミオシン (骨格筋および平滑筋型) ウサギ宿主抗体

whole antiserum

• MDL番号: MFCD00162703
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: whole antiserum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 含みます: 15 mM sodium azide
• 化学種の反応性: animal, human
• テクニック: indirect immunofluorescence: 1:10 using cultured fibroblasts
• UniProtアクセッション番号: P35579; P35580
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MYH10(4628) , MYH9(4627) , MYL9(10398)

詳細

詳細

Myosin is a 500 kD protein that interacts with actin in muscle and in non-muscle cells. It is characterized with two identical heavy chains (200 kD each) and four light chains (15-20 kD each). Myosin molecules consist of two major regions; the tail (rod) and head. These molecules aggregate into filaments through the tail region and interact with actin and ATP through the head region.

特異性

培養ヒトおよび動物繊維芽細胞のストレスファイバ-に沿った染色パタ-ンが認められます。

免疫原

ウシ子宮由来ミオシン全分子(H鎖およびL鎖)。

アプリケーション

Anti-Myosin (Skeletal and Smooth) antibody produced in rabbit has been used in indirect immunofluorescence labeling.

生物化学的／生理学的作用

Myosin plays a vital role in neurosensory and cortical function, membrane vesicle trafficking and determinant partitioning. Myosins with actin-stimulated ATPase activity is essential for various cellular movements. Myosins I and V mediates vesicle translocation. Myosin II with a long rod like tail domain, assembles into a bipolar thick filament and facilitate muscle contraction.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable