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Merck

M1272

Sigma-Aldrich

抗マウスIgA (α-鎖特異的) ヒツジ宿主抗体

affinity isolated antibody, lyophilized powder

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

sheep

品質水準

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

secondary antibodies

クローン

polyclonal

フォーム

lyophilized powder

テクニック

Ouchterlony double diffusion: suitable

保管温度

2-8°C

ターゲットの翻訳後修飾

unmodified

詳細

IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces
Anti-Mouse IgA (α-chain specific) is specific for α chain of mouse IgA.

免疫原

Purified mouse IgA (myeloma protein)

アプリケーション

Anti-Mouse IgA (α-chain specific) is suitable for Ouchterlony Double Diffusion. The antibody was used to detect antigens to Helicobacter hepaticus in mice serum using a concentration of 5 μg/ml.

物理的形状

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2

再構成

Reconstitute with 0.135 M sodium chloride.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Mark T Whary et al.
Immunology, 133(2), 165-178 (2011-03-24)
To model inflammatory bowel disease, we assessed infection with Helicobacter hepaticus 3B1 (ATCC 51449) and a potential probiotic Lactobacillus reuteri (ATCC PTA-6475) in gnotobiotic B6.129P2-IL-10(tm1Cgn) (IL-10(-/-) ) mice. No typhlocolitis developed in germ-free controls (n=21) or in L. reuteri (n=8)
Jan Holmgren et al.
Nature medicine, 11(4 Suppl), S45-S53 (2005-04-07)
There is currently great interest in developing mucosal vaccines against a variety of microbial pathogens. Mucosally induced tolerance also seems to be a promising form of immunomodulation for treating certain autoimmune diseases and allergies. Here we review the properties of
Veronica Rainone et al.
PloS one, 6(10), e26979-e26979 (2011-11-09)
Mucosae-associated epithelial chemokine (MEC or CCL28) binds to CCR3 and CCR10 and recruits IgA-secreting plasma cells (IgA-ASCs) in the mucosal lamina propria. The ability of this chemokine to enhance migration of IgA-ASCs to mucosal sites was assessed in a mouse

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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