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由来生物
mouse
品質水準
結合体
unconjugated
抗体製品の状態
ascites fluid
抗体製品タイプ
secondary antibodies
クローン
HP-6054, monoclonal
含みます
15 mM sodium azide
テクニック
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: 1:1,000 using using 2 μg/ml of human IgG myeloma containing lambda light chains as the coating protein
radioimmunoassay: suitable
western blot: suitable
アイソタイプ
IgG2a
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
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詳細
Monoclonal Anti-Human Lambda Light Chains (mouse IgG2a isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Immunoglobulins are composed of two heavy and two light polypeptide chains held together by noncovalent forces and usually by interchain disulfide bridges. The various types of human (and other mammalian) immunoglobulins contain one of the two existing light chain types, either κ or λ in which multiple structural differences are reflected in antigenic variety, mainly the N-terminal (variable) domain of the chains.
特異性
The antibody is specific for human lambda (λ) light chains. This antibody is reactive with intact IgG (λ), IgA (λ), free lambda light chains and Bence-Jones lambda light chains. It is non-reactive with kappa light chains.
免疫原
Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads.
アプリケーション
Monoclonal Anti-Human Lambda Light Chains (Bound and Free) antibody produced in mouse has been used:
- in immunohistochemistry
- in enzyme-linked immunosorbent assay (ELISA) assay
- in immunohistology
- in radioimmunoassay (RIA)
- in precipitation assays
- in immunoblotting
- as capture antibodies in quantitative ELISA
生物化学的／生理学的作用
Immunoglobulins (Ig) are produced by the B cells and play crucial role in host humoral immune response. A typical immunoglobulin consists of two heavy chains and two light chains. The two light chains are either κ or the λ chain. The B cells express one type of light chain during their life time.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
L6522-VAR:
L6522-.5ML:
L6522-.2ML:
L6522-BULK:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Primary lymphoma of the central nervous system: a clinical-pathological and immunohistochemical study of ten autopsy cases
Costa H, et al.
Arquivos de Neuro-Psiquiatria, 64(4), 976-982 (2006)
A human immunoglobulin lambda locus is similarly well expressed in mice and humans
Popov AV, et al.
The Journal of Experimental Medicine, 189(10), 1611-1620 (1999)
J E M Gilmour et al.
Transfusion medicine (Oxford, England), 18(3), 167-174 (2008-07-05)
The aim of this study was to determine the effect of expressing a recombinant anti-Kell immunoglobulin (Ig) M from two cell lines, CH0 and NS0, on its ability to function as a diagnostic antibody. As a polymeric immunoglobulin, IgM is
Patrizia Circelli et al.
Bioengineered bugs, 1(3), 221-224 (2011-02-18)
We have recently described an efficient transient expression system mediated by Agrobacterium tumefaciens for the production of HIV-1 Nef protein in Nicotiana benthamiana plants. In order to enhance the yield of recombinant protein we assayed the effect of three gene-silencing
Maria Elena Villani et al.
Plant biotechnology journal, 7(1), 59-72 (2008-09-17)
The aims of this work were to obtain a human antibody against the tumour-associated antigen tenascin-C (TNC) and to compare the yield and quality of plant-produced antibody in either stable transgenics or using a transient expression system. To this end
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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