L4417

Anti-phospho-Lck (pTyr¹⁹²) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

• MDL番号: MFCD06798494
• UNSPSCコード: 12352203
• NACRES: NA.44

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous glycerol solution
• 化学種の反応性: human
• テクニック: western blot: 1:1,000 using full length recombinant human Lck protein.
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pTyr192)
• 遺伝子情報: human ... LCK(3932) ; mouse ... Lck(16818)

詳細

詳細

Lck, also referred to as T cell-specific protein tyrosine kinase, is a 56kD protein that belongs to Src family of non-receptor tyrosine protein kinases and is expressed mainly in T cells. It has a pivotal role in the initiation of pre-TCR and T-cell antigen receptor (TCR)-linked signal transduction pathways. Anti-phospho-Lck (pTyr192) antibody reacts specifically with Lck (pTyr192) in humans.

免疫原

synthetic phosphopeptide derived from the region of Lck that is phosphorylated on tyrosine 192. Human and mouse have 100% homology.

アプリケーション

Anti-phospho-Lck (pTyr192) antibody can be used in western blotting (diluted 1:1000) using full length recombinant human Lck protein.

物理的形状

Solution in Dulbecco′s phosphate buffered saline (without Mg²⁺ and Ca²⁺), pH 7.3 (+/- 0.1), 50% glycerol, with 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide.

調製ノート

The antibody is preadsorbed to remove any reactivity towards a non-phosphorylated Lck.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)