F8053

Anti-FADD antibody, Mouse monoclonal

clone FD19, purified from hybridoma cell culture

• 別名: Anti-Fas Associated Death Domain
• MDL番号: MFCD01633337
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: FD19, monoclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~28 kDa
• 化学種の反応性: human
• 濃度: ~2 mg/mL
• テクニック: immunoprecipitation (IP): suitable; indirect ELISA: suitable; microarray: suitable; western blot: 0.5-1 μg/mL using total cell extracts of A431 cells
• アイソタイプ: IgG1
• UniProtアクセッション番号: Q13158
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... FADD(8772)

詳細

詳細

Anti-FADD antibody, Mouse monoclonal (mouse IgG1) is derived from the FD19 hybridoma produced by the fusion of murine myeloma cells (NS1) and splenocytes from mouse immunized with purified recombinant human FADD.

免疫原

精製リコンビナントヒトFADD。

アプリケーション

Anti-FADD antibody, Mouse monoclonal has been used in:

• immunoblotting
• immunoprecipitation
• enzyme-linked immunosorbent assay (ELISA)

生物化学的／生理学的作用

FADD (Fas Associated Death Domain) is associated with various non-apoptotic cellular pathways such as regulation of cell cycle machinery in T lymphocytes connected to the phosphorylation state of FADD and to the FasL/TRAIL-induced transcriptional activation of c-fos protooncogene. It also interacts with the hepatitis C virus core protein in the HEK-293 cell line.

物理的形状

0.01 M PBS溶液(pH 7.4, 15 mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)