E3539

プロテイナーゼ3 ヒト白血球由来

≥95% (PAGE)

• 別名: プロテイナーゼ 3 ヒト白血球由来, PR3 Ag
• Enzyme Commission number: 3.4.21.76 (BRENDA, IUBMB)
• MDL番号: MFCD03458212
• UNSPSCコード: 12352204
• NACRES: NA.54

特性

• アッセイ: ≥95% (PAGE)
• フォーム: buffered aqueous solution
• UniProtアクセッション番号: P24158
• 保管温度: −20°C
• 遺伝子情報: human ... PRTN3(5657)

詳細

詳細

Proteinase 3 is found in high concentration in the primary granules of myeloid leukemia blasts.⁴

アプリケーション

Proteinase 3 has been shown to be important in the pathogenesis of human emphysema.¹ It has also been used in a study to investigate the liberation of the antibacterial and cytotoxic peptide LL-37 by cleavage of human cathelicidin hCAP-183.²

生物化学的／生理学的作用

イムノアッセイでの抗PR3自己抗体の検出に用いられます。

Proteinase 3 (PR-3) is a serine protease expressed in the granules of neutrophils and monocytes. Also known as myeloblastin and p29b, it degrades elastin and is associated with myeloid leukemia and Wegener′s granulomatosis.³

物理的形状

Solution in 50 mM sodium acetate (pH 5) with 600 mM sodium chloride

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable