C8863

7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine

≥98% (HPLC)

• 実験式（ヒル表記法）: C₂₃H₂₂N₄O
• CAS番号: 213743-31-8
• 分子量: 370.45
• MDL番号: MFCD04974490
• UNSPSCコード: 12352116
• PubChem Substance ID: 24278409
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white
• 溶解性: DMSO: soluble 17 mg/mL at ≤60 °C
• 保管温度: 2-8°C
• SMILES記法: Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)C5CCCC5
• InChI: 1S/C23H22N4O/c24-22-21-20(14-27(17-6-4-5-7-17)23(21)26-15-25-22)16-10-12-19(13-11-16)28-18-8-2-1-3-9-18/h1-3,8-15,17H,4-7H2,(H2,24,25,26)
• InChI Key: FMETVQKSDIOGPX-UHFFFAOYSA-N
• 遺伝子情報: human ... KDR(3791) , LCK(3932) , TEK(7010)

詳細

生物化学的／生理学的作用

A potent and selective pyrrolo[2,3-d]pyrimidine Lck inhibitor.

Potent and selective inhibitor of Lck, a src family tyrosine kinase.

特徴および利点

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安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)