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詳細
CTB (N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide) is derived from anacardic acid.
アプリケーション
CTB has been used to study its apoptotic effects on P53 protein acetylation.
生物化学的／生理学的作用
CTPBは、ヒストンアセチルトランスフェラーゼp300のアクチベーターとして初めて知られた低分子化合物です。CTBは、CTPBと同程度かあるいはそれ以上の活性を発揮するCTPBの単純化アナログです。この化合物は、p300/EP300/E1A結合タンパク質のHAT活性を賦活化します。現在、その他HATアクチベーターは取り扱っておりません。
Small molecule activators of HAT such as CTB (N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide) is useful for altering chromatin acetylation directly. It might serve as a therapeutic agent for treating the complications of cognitive dysfunction including neuropsychiatric, neurodevelopmental and neurodegenerative diseases.
特徴および利点
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
保管分類コード
11 - Combustible Solids
WGK
WGK 2
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
C6499-25MG:
C6499-VAR:
C6499-BULK:
C6499-5MG:
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資料
Epigenetic modifications are thought to occur through two key interconnected processes—DNA methylation and the covalent modification of histones.
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