C4695

CHAPSO

BioXtra

• 別名: 3-[(3-コラミドプロピル)ジメチルアンモニオ]-2-ヒドロキシ-1-プロパンスルホナート
• 実験式（ヒル表記法）: C₃₂H₅₈N₂O₈S
• CAS番号: 82473-24-3
• 分子量: 630.88
• Beilstein: 5842642
• MDL番号: MFCD00081079
• UNSPSCコード: 12161900
• PubChem Substance ID: 24892713
• NACRES: NA.25

特性

• 詳細: zwitterionic
• 品質水準: 200
• 製品種目: BioXtra
• アッセイ: ≥98.0% (TLC)
• 形状: powder
• 分子量: micellar avg mol wt 7000
• 凝集数: 11
• 不純物: ≤0.0005% Phosphorus (P); ≤0.1% Insoluble matter (in Ethanol)
• 強熱残分: ≤0.1%
• CMC: 8 mM (20-25°C); 8 mM (micellar weight =9960)
• mp: 184-186 °C (lit.)
• 転移温度: cloud point 90 °C
• 溶解性: H₂O: 0.1 M °C, clear, colorless
• 微量陰イオン: chloride (Cl^-): ≤0.05%; sulfate (SO₄^2-): ≤0.05%
• 微量陽イオン: Al: ≤0.0005%; Ca: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH₄⁺: ≤0.05%; Na: ≤0.01%; Pb: ≤0.001%; Zn: ≤0.0005%
• SMILES記法: [H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCC[N+](C)(C)CC(O)CS([O-])(=O)=O
• InChI: 1S/C32H58N2O8S/c1-20(7-10-29(39)33-13-6-14-34(4,5)18-23(36)19-43(40,41)42)24-8-9-25-30-26(17-28(38)32(24,25)3)31(2)12-11-22(35)15-21(31)16-27(30)37/h20-28,30,35-38H,6-19H2,1-5H3,(H-,33,39,40,41,42)/t20-,21+,22-,23?,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
• InChI Key: GUQQBLRVXOUDTN-XOHPMCGNSA-N

詳細

詳細

Chapso is a zwitterionic detergent derived from Chaps by the addition of a functional hydroxyl group. It is a nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group.

アプリケーション

Chapso has been used in a study to assess methods for high-throughput crystallization of membrane proteins. It has also been used in a study to investigate the effects of detergents on the structure of rhomboid proteases in a lipid environment.

CHAPSと類似の特性を有する非変性両性界面活性剤です。ただし、CHAPSよりも極性頭部基が多いため、より高い溶解性を示します。内在性膜タンパク質を溶解させるのに有用です。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves