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製品名
骨形成タンパク質4 ヒト, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
由来生物
human
品質水準
リコンビナント
expressed in NSO cells
アッセイ
>95% (SDS-PAGE)
フォーム
lyophilized powder
有効性
10-30 ng/mL ED50
分子量
monomer calculated mol wt 13 kDa
~22 kDa by SDS-PAGE
包装
pkg of 10 μg
保管条件
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
テクニック
cell culture | mammalian: suitable
不純物
<1 EU/mg Endotoxin level (LAL test)
UniProtアクセッション番号
保管温度
−20°C
遺伝子情報
human ... BMP4(652)
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生物化学的／生理学的作用
BMP-4に対する細胞応答は、セリン/スレオニンキナーゼレセプターI型とII型のヘテロオリゴマー複合体形成によって仲介されています。BMP類は骨芽細胞によるVEGF-A産生を引き起こすことにより、血管形成を刺激します。成熟ラットBMP-4に対する成熟ヒトおよびマウスBMP-4のホモロジーは、それぞれ98%、100%です。
物理的形状
凍結乾燥品(30%アセトニトリルおよび0.1%TFA溶液, サイトカイン1μg当たり50μg BSA含有, 0.2μmフィルタ-ろ過滅菌済み)
アナリシスノート
生物活性は、 C2C12筋芽細胞によるアルカリホスファタ-ゼ産生の誘導能で測定しています。
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
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資料
Cancer stem cell media, spheroid plates and cancer stem cell markers to culture and characterize CSC populations.
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