AV44817

抗RHOT1抗体 ウサギ宿主抗体

affinity isolated antibody

• 別名: Anti-Ras ホモログ遺伝子ファミリー T1抗体, 抗ARHT1抗体, 抗FLJ11040抗体, 抗FLJ12633抗体, 抗MIRO-1抗体
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 抗体製品の状態: affinity isolated antibody
• 品質水準: 100
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: 71 kDa
• 交差性: rabbit, horse, bovine, rat, human, mouse, guinea pig, dog
• 濃度: 0.5 mg - 1 mg/mL
• テクニック: immunohistochemistry: suitable; western blot: suitable
• NCBIアクセッション番号: NP_060777
• UniProtアクセッション番号: Q8IXI2
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... RHOT1(55288)

詳細

詳細

Anti-RHOT1 polyclonal antibody reacts with RHOT1 in chicken, bovine, human, zebrafish, pig, rat, canine, and mouse.

Ras homolog gene family, member T1 (RHOT1, MIRO-1) is an atypical Rho GTPase involved in calcium sensitive mitochondrial trafficking. Miro interacts with the kinesin-binding proteins GRIF-1 and OIP106 forming a link between the mitochondria and the trafficking apparatus of the microtubules. Miro1 and the kinesin adaptor Grif-1 play an important role in regulating mitochondrial transport in neurons. Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

免疫原

Synthetic peptide directed towards the N terminal region of human RHOT1

アプリケーション

Anti-RHOT1 polyclonal antibody is suitable for use in western blotting and immunohistochemical (IHC) techniques. The antibody is used as a probe to determine the role of RHOT1 in calcium-sensitive mitochondrial trafficking.

生物化学的／生理学的作用

Mitochondrial GTPase involved in mitochondrial trafficking. RHOT1 is probably involved in control of anterograde transport of mitochondria and their subcellular distribution.

シーケンス

Synthetic peptide located within the following region: MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPER

物理的形状

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable