A4475

Anti-Annexin VII antibody, Mouse monoclonal

clone 203-217/6, purified from hybridoma cell culture

• 別名: Synexin
• MDL番号: MFCD03792412
• UNSPSCコード: 12352203
• NACRES: NA.44
• 結合体: unconjugated
• application: ARR; ICC; IHC (f); WB
• クローン: 203-217/6, monoclonal
• 化学種の反応性: mouse, canine, rat, chicken, bovine, human, rabbit
• citations: 5
• テクニック: immunocytochemistry: suitable using methanol or 1% paraformaldehyde/0.1% glutaraldehyde; immunohistochemistry (frozen sections): suitable; microarray: suitable; western blot: 0.5-1 μg/mL using whole cell extract of culture mouse connective tissue (A9) cells.

特性

• 由来生物: mouse
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 203-217/6, monoclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 47-51 kDa
• 化学種の反応性: mouse, canine, rat, chicken, bovine, human, rabbit
• テクニック: immunocytochemistry: suitable using methanol or 1% paraformaldehyde/0.1% glutaraldehyde; immunohistochemistry (frozen sections): suitable; microarray: suitable; western blot: 0.5-1 μg/mL using whole cell extract of culture mouse connective tissue (A9) cells.
• アイソタイプ: IgG1
• UniProtアクセッション番号: P20073
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ANXA7(310) ; mouse ... Anxa7(11750) ; rat ... Anxa7(155423)

詳細

詳細

Annexin VII (synexin) is a membrane binding protein that localizes in the nucleus and cytosol. In humans and mice, Annexin VII is encoded by a single gene that has alternatively spliced cassette exons. As a result, two isoforms of molecular mass of 47kDa and 51kDa are expressed. These isoforms differ in their N-terminal region and also have distinct tissue-specific expression patterns.

Anti-Annexin VII antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the 203-217/6 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a recombinant mouse Annexin VII. The human annexin VII (ANXA7) is located on chromosome 10q21.

特異性

Mouse monoclonal anti-annexin VII antibody reacts with human, bovine, rabbit, dog, rat, mouse, and chicken Annexin VII.

免疫原

recombinant mouse annexin VII.

アプリケーション

Anti-Annexin VII antibody, Mouse monoclonal has been used in:

• western blotting
• immunocytochemistry
• immunohistochemistry

生物化学的／生理学的作用

Antibodies reacting specifically with Annexin VII serve as an essential tool for the detection of this molecule in various cells. The human annexin VII (ANXA7) possesses a tumor suppressor role in prostate cancer. Hence it can be used an important biomarker along with syndecan-1 to predict the survival rates in prostate cancer patients.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable