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安全性情報

A3813

Sigma-Aldrich

抗ヒトκL鎖(結合型・遊離型)抗体-アルカリホスファターゼ標識 ヤギ宿主抗体

affinity isolated antibody, buffered aqueous glycerol solution

別名:

Goat Anti-Human Kappa Light Chains (Bound and Free)−AP

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

goat

結合体

alkaline phosphatase conjugate

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

secondary antibodies

クローン

polyclonal

フォーム

buffered aqueous glycerol solution

交差性

human

テクニック

direct ELISA: 1:30,000
dot blot: 1:30,000
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50

輸送温度

wet ice

保管温度

2-8°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... IGK@(50802)

詳細

Human κ light chains are antibody fragments that regulate immunological responses in cells. Increased expression of κ light chains has been linked to chronic lymphocytic leukemia . The variable fragment of the κ light chain gene has also been associated with vaccine-induced antibody response to the polysaccharide coat in Haemophilus influenzae type b . Anti-Human κ Light Chains (Bound and Free-Alkaline Phosphatase antibody is specific for human κ light chain when tested against human IgA, IgG, IgM, IgGλ, IgAλ, IgMλ, Bence Jones κ and λ myeloma proteins.

免疫原

Purified Bence Jones κ light chain

アプリケーション

Anti-Human κ Light Chains (Bound and Free)-Alkaline Phosphatase antibody is suitable for use in ELISA. The product can also be used for dot blot (1:30,000) and immunohistochemistry (1:50 using formalin-fixed, paraffin-embedded sections).
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Mouse-Human chimeric IgG′s specific for Pseudomonas aeruginosa serogroup 06 lipopolysaccharide were identified by ELISA in transfected CHO cell supernatants using Alkaline phosphatase conjugated goat anti-Human Kappa Light chains.

物理的形状

0.05 M Trisバッファ-溶液(pH 8.0, 1 mM MgCl2, 10 mMグリシン, 1%BSA, 50%グリセロ-ル, 15 mMアジ化ナトリウム含有)

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

A3813-VAR:
A3813-1ML:
A3813-.5ML:
A3813-BULK:
A3813-.25ML:
A3813PROC:


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文書ライブラリにアクセスする

Leif Kofoed Nielsen et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 114(5), 345-351 (2006-05-27)
For over 35 years hemolytic disease of the fetus and newborn (HDFN) due to RhD has been effectively prevented by anti-RhD antibodies obtained from alloimmunized women or deliberately immunized men. However, due to the reduced number of immunized women and
Lisa A Pieper et al.
Metabolic engineering, 40, 69-79 (2017-01-16)
Chinese Hamster Ovary (CHO) cells are the most commonly used host for the production of biopharmaceuticals. Although transcription and translation engineering strategies have been employed to generate high-producer cell clones, the secretory pathway still remains a bottleneck in cellular productivity.
Fusion Proteins of Single-Chain Variable Fragments Derived from Phage Display Libraries Are Effective Reagents for Routine Diagnosis of Potato Leafroll Virus Infection in Potato
Toth, R., L., et al.
Virology, 89(11), 1015-1021 (1999)
Rogier A van Dijk et al.
Journal of lipid research, 53(12), 2773-2790 (2012-09-13)
The relationships between oxidation-specific epitopes (OSE) and lipoprotein (a) [Lp(a)] and progressive atherosclerosis and plaque rupture have not been determined. Coronary artery sections from sudden death victims and carotid endarterectomy specimens were immunostained for apoB-100, oxidized phospholipids (OxPL), apo(a), malondialdehyde-lysine
Thomas Bouquin et al.
Transgenic research, 11(2), 115-122 (2002-06-11)
Transgenic plants represent an alternative to cell culture systems for producing cheap and safe antibodies for diagnostic and therapeutic use. To evaluate the functional properties of a 'plantibody', we generated transgenic Arabidopsis plants expressing full-length human IgG1 against the Rhesus

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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