おすすめの製品
由来生物
mouse
品質水準
100
500
結合体
unconjugated
抗体製品の状態
culture supernatant
抗体製品タイプ
primary antibodies
クローン
DO7, monoclonal
詳細
For In Vitro Diagnostic Use in Select Regions (See Chart)
形状
buffered aqueous solution
化学種の反応性
human
包装
vial of 0.1 mL concentrate (453M-94)
vial of 0.5 mL concentrate (453M-95)
bottle of 1.0 mL predilute (453M-97)
vial of 1.0 mL concentrate (453M-96)
bottle of 7.0 mL predilute (453M-98)
メーカー／製品名
Cell Marque™
テクニック
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
アイソタイプ
IgG2bκ
コントロール
colon carcinoma
輸送温度
wet ice
保管温度
2-8°C
視覚化
nuclear
遺伝子情報
human ... TP53(7157)
詳細
Anti-p53 tumor suppressor protein recognizes a 53 kDa hosphoprotein, identified as a p53 suppressor gene product. It reacts with the mutant as well as wild form of p53. Positive nuclear staining with this antibody has been shown to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
品質
 IVD |  IVD |  IVD |  RUO |
関連事項
p53 Positive Control Slides, Product No. 453S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
物理的形状
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
調製ノート
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
その他情報
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法的情報
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications (2002)
B E Moore et al.
Applied immunohistochemistry & molecular morphology : AIMM, 9(3), 203-206 (2001-09-15)
Intratubular germ cell neoplasia, unclassified (IGCNU) is a precursor of germ cell tumors (GCT) of the testis. In routine histologic sections, neoplastic intratubular germ cells may be very few and easily overlooked. The aim of this study is two-fold: to
C Midulla et al.
Anticancer research, 19(5B), 4033-4037 (2000-01-11)
The different clinical evolution of breast cancer with similar pathological characteristics prompted the authors to investigate the prognostic significance of different biological markers. Seventy-one primary breast carcinoma specimens obtained by mastectomy or quadrantectomy were examined for the determination of the
F A Mauri et al.
International journal of oncology, 15(6), 1137-1147 (1999-11-24)
Steroid receptor analysis is the only widely accepted prognostic/predictive marker in breast cancer (BC) treatment. In the present study we evaluated the prognostic role of ER/PgR with p53 and Bcl2, in a series of 277 BC (153 pN1/2, 122 pNO
D C Quinlan et al.
Cancer research, 52(17), 4828-4831 (1992-09-01)
Mutations in the gene coding for the p53 tumor suppressor protein are common in a variety of human cancers. To assess the role of a putative mutated p53 protein in human lung cancer, a monoclonal antibody recognizing it was used
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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