42602

Propionyl-L-carnitine

≥94.0% (HPLC), suitable for LC/MS

• 別名: (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine propionyl ester, C3-Carnitine, Propanoyl-L-carnitine
• 実験式（ヒル表記法）: C₁₀H₁₉NO₄
• CAS番号: 20064-19-1
• 分子量: 217.26
• MDL番号: MFCD00870024
• UNSPSCコード: 12352209
• PubChem Substance ID: 329756246
• NACRES: NA.26

特性

• product name: Propionyl-L-carnitine, ≥94.0% (HPLC)
• 品質水準: 100
• アッセイ: ≥94.0% (HPLC)
• 形状: powder or crystals
• 光学活性: [α]/D -23±3°, c = 1 in H₂O
• テクニック: LC/MS: suitable
• 不純物: ≤10% water (calcd. from elemental analysis)
• 色: white to off-white
• 保管温度: 2-8°C
• SMILES記法: [O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
• InChI: 1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
• InChI Key: UFAHZIUFPNSHSL-MRVPVSSYSA-N

詳細

詳細

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

アプリケーション

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

生物化学的／生理学的作用

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable