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Key Documents

271M-1

Sigma-Aldrich

Inhibin, alpha (R1) Mouse Monoclonal Antibody

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

mouse

品質水準

100
500

結合体

unconjugated

抗体製品の状態

culture supernatant

抗体製品タイプ

primary antibodies

クローン

R1, monoclonal

詳細

For In Vitro Diagnostic Use in Select Regions (See Chart)

形状

buffered aqueous solution

化学種の反応性

human

包装

vial of 0.1 mL concentrate (271M-14)
vial of 0.5 mL concentrate (271M-15)
bottle of 1.0 mL predilute (271M-17)
vial of 1.0 mL concentrate (271M-16)
bottle of 7.0 mL predilute (271M-18)

メーカー/製品名

Cell Marque

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:5-1:100

アイソタイプ

IgG2a

コントロール

adrenal cortex

輸送温度

wet ice

保管温度

2-8°C

視覚化

cytoplasmic

遺伝子情報

human ... INHA(3623)

詳細

Anti–inhibin alpha is an antibody against a peptide hormone which has demonstrated utility in the differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastc tumors also demonstrate cytoplasmic positivity with this antibody. This antibody has been used to make the differential diagnosis of intrauterine vs. ectopic pregnancy in endometrial curettings.

品質


IVD

IVD

IVD

RUO

関連事項

Inhibin, alpha Positive Control Slides, Product No. 271S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

P A Fetsch et al.
Cancer, 87(3), 168-172 (1999-06-29)
Anti-alpha-inhibin, an antibody directed against a peptide hormone, has been shown to be a useful diagnostic aid in surgical pathology material for the identification of sex cord-stromal neoplasms and recently has been described in adrenocortical carcinoma (ACC). The diagnosis of
T J Pelkey et al.
Human pathology, 30(1), 26-31 (1999-01-29)
Placental trophoblasts are the primary source of serum inhibin during pregnancy. We sought to characterize inhibin immunolabeling in trophoblastic neoplasms and compare the results with those for established markers of trophoblastic differentiation. Formalin-fixed, paraffin-embedded tissues from three normal term placentas
W G McCluggage
Journal of clinical pathology, 53(5), 327-334 (2000-07-13)
This leader reviews recent advances in immunohistochemistry that are useful in the diagnosis of ovarian neoplasms. These include the value of different anticytokeratin antibodies in the distinction between a primary ovarian adenocarcinoma and a metastatic adenocarcinoma, especially of colorectal origin.
C J Stewart et al.
Histopathology, 31(1), 67-74 (1997-07-01)
Inhibin is a heterodimeric protein hormone which appears to be a sensitive serological and immunohistochemical marker of ovarian granulosa cell tumours. The purposes of this study were to examine inhibin immunoreactivity in a wide range of gonadal stromal neoplasms and
L M Munro et al.
The Journal of endocrinology, 161(2), 341-347 (1999-05-13)
Inhibins and activins are dimeric proteins of the transforming growth factor-beta superfamily which have been shown to be expressed in the adrenal cortex. Recent studies have suggested a role for these peptides in the pathogenesis and/or function of adrenal tumours.

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