おすすめの製品
由来生物
mouse
品質水準
100
500
結合体
unconjugated
抗体製品の状態
culture supernatant
抗体製品タイプ
primary antibodies
クローン
ALK-1, monoclonal
詳細
For In Vitro Diagnostic Use in Select Regions (See Chart)
フォーム
buffered aqueous solution
化学種の反応性
human
包装
vial of 0.1 mL concentrate (204M-14)
vial of 0.5 mL concentrate (204M-15)
bottle of 1.0 mL predilute (204M-17)
vial of 1.0 mL concentrate (204M-16)
bottle of 7.0 mL predilute (204M-18)
メーカー／製品名
Cell Marque®
テクニック
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
アイソタイプ
IgG3κ
コントロール
anaplastic large cell lymphoma
輸送温度
wet ice
保管温度
2-8°C
視覚化
cytoplasmic, nuclear
詳細
ALK-1 is a novel fusion protein which is detected in 60% of Anaplastic Large Cell Lymphomas and has proven to indicate improved prognosis in the ALK-1 (+) group.
品質
 IVD |  IVD |  IVD |  RUO |
関連事項
ALK Protein Positive Control Slides, Product No. 204S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
物理的形状
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
調製ノート
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
その他情報
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法的情報
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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最新バージョンのいずれかを選択してください：
B Falini et al.
The American journal of pathology, 153(3), 875-886 (1998-09-15)
The t(2;5)(p23;q35) translocation associated with CD30-positive anaplastic large cell lymphoma results in the production of a NPM-ALK chimeric protein, consisting of the N-terminal portion of the NPM protein joined to the entire cytoplasmic domain of the neural receptor tyrosine kinase
S Nakamura et al.
The American journal of surgical pathology, 21(12), 1420-1432 (1997-12-31)
The p80(NPM/ALK) expression activated by the t(2;5) (p23;q35) translocation recently has been shown to play an important role in the pathogenesis of anaplastic large cell lymphoma (ALCL). However, the clinicopathologic significance of identification of p80 among ALCL cases has not
K A Cataldo et al.
The American journal of surgical pathology, 23(11), 1386-1392 (1999-11-11)
Anaplastic large cell lymphoma (ALCL) is associated with the t(2;5)(p23;q35) translocation involving the anaplastic lymphoma kinase gene (ALK) and the nucleophosmin gene (NPM), which result in expression of a novel fusion protein, NPM-ALK (p80). Clinicopathologic studies have shown that ALK
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