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Merck
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Key Documents

安全性情報

120R-1

Sigma-Aldrich

CD20 (SP32) Rabbit Monoclonal Antibody

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

100
500

結合体

unconjugated

抗体製品の状態

culture supernatant

抗体製品タイプ

primary antibodies

クローン

SP32, monoclonal

詳細

For In Vitro Diagnostic Use in Select Regions (See Chart)

形状

buffered aqueous solution

化学種の反応性

human

包装

vial of 0.1 mL concentrate (120R-14)
vial of 0.5 mL concentrate (120R-15)
bottle of 1.0 mL predilute (120R-17)
vial of 1.0 mL concentrate (120R-16)
bottle of 7.0 mL predilute (120R-18)

メーカー／製品名

Cell Marque™

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

アイソタイプ

IgG1

コントロール

tonsil

輸送温度

wet ice

保管温度

2-8°C

視覚化

membranous

詳細

Anti-CD20 (pan B-cell) reacts with a membrane antigen that is present in B-cells as this epitope is acquired late in the pre-B-cell stage of maturation and remains on cells throughout most of the differentiation process, although it is lost at the plasma cell stage. This antibody recognizes Reed-Sternberg cells, predominant in classic Hodgkin′s disease, in approximately 20% of cases, and approximately half of lymphoblastic lymphoma/leukemias. Since no staining of histiocytes or plasma cells has been observed and CD20 has rarely been detected in T-cell malignancies, it is a dependable marker of B-cell lymphomas. Anti-CD20 does not cross-react with non-hematopoetic neoplasms.

関連事項

CD20 Positive Control Slides, Product No. 120S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

120R-18-RUO:
120R-16-RUO:
120R-17:
120R-17-RUO:
120R-15-RUO:
120R-15:
120R-16:
120R-12:
120R-14-RUO:
120R-14:
120R-11:
120R-18:
120R-13:

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

P Korkolopoulou et al.
Histopathology, 24(6), 511-515 (1994-06-01)
Recent evidence indicates that membrane-bound immunoglobulin on B lymphocytes is associated with a molecule which comprises the products of the mb-1 and B29 genes. This molecule is a highly specific marker for B-cells, presumably because of its central functional role
G S Pinkus et al.
The American journal of pathology, 133(2), 211-217 (1988-11-01)
Immunoreactivity for L26, a highly effective pan B cell marker that can be detected in paraffin sections, was evaluated in 72 cases of Hodgkin's disease of various histologic types. In all cases of nodular lymphocyte predominance type of Hodgkin's disease
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications (2006)
A L Epstein et al.
Journal of immunology (Baltimore, Md. : 1950), 133(2), 1028-1036 (1984-08-01)
Two monoclonal antibodies (LN-1, LN-2) reactive with B lymphocytes in B5 formalin-fixed, paraffin-embedded tissue sections have been produced by utilizing cell extracts from pokeweed mitogen-stimulated peripheral blood lymphocytes and diffuse histiocytic lymphoma SU-DHL-4 cells, respectively. Both monoclonal antibodies were initially
R J Marder et al.
Laboratory investigation; a journal of technical methods and pathology, 52(5), 497-504 (1985-05-01)
Monoclonal antibodies (MoAbs) to B cell- and T cell-specific antigens uniformly have been restricted in their use to cell suspension or frozen section techniques because the antigens that they identify are either masked or lost in the fixation or paraffin-embedding

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