10385

アンジオテンシン III トリフルオロアセタート塩 水和物

≥98% (HPCE)

• 別名: Des-Asp-1-アンジオテンシンII トリフルオロアセタート塩 水和物
• 実験式（ヒル表記法）: C₄₆H₆₆N₁₂O₉ · xC₂HF₃O₂ · yH₂O
• CAS番号: 12687-51-3
• 分子量: 931.09 (anhydrous free base basis)
• Beilstein: 8385695
• MDL番号: MFCD20264812
• UNSPSCコード: 12352200
• PubChem Substance ID: 57646800
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPCE)
• 溶解性: H₂O: 1.0 mg/mL, clear, colorless
• 保管温度: −20°C
• SMILES記法: O.OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(N)=N)C(C)C)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc4ccccc4)C(O)=O
• InChI: 1S/C46H66N12O9.C2HF3O2.H2O/c1-5-27(4)38(57-40(61)33(21-29-15-17-31(59)18-16-29)53-42(63)37(26(2)3)56-39(60)32(47)13-9-19-51-46(48)49)43(64)54-34(23-30-24-50-25-52-30)44(65)58-20-10-14-36(58)41(62)55-35(45(66)67)22-28-11-7-6-8-12-28;3-2(4,5)1(6)7;/h6-8,11-12,15-18,24-27,32-38,59H,5,9-10,13-14,19-23,47H2,1-4H3,(H,50,52)(H,53,63)(H,54,64)(H,55,62)(H,56,60)(H,57,61)(H,66,67)(H4,48,49,51);(H,6,7);1H2/t27-,32-,33-,34-,35-,36-,37-,38-;;/m0../s1
• InChI Key: JEOAJMGVSAMVML-UFPGTABSSA-N

詳細

Amino Acid Sequence

Arg-Val-Tyr-Ile-His-Pro-Phe

詳細

Angiotensin III (Ang III) is a 7-AA bioactive peptide that is formed from the degradation of the Angiotensin II peptide by aminopeptidase A; both are derivatives of angiotensinogen and are components of the renin-angiotensin system (RAS).

生物化学的／生理学的作用

Angiotensin III is an AT₁ and AT₂ agonist, with higher sensitivity for the AT₂ receptor. Ang III has been shown to be a main effector peptide in RAS-controlled vasopresin release and a stimulator for aldosterone release.

特徴および利点

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

抗体吸着処理

Arg-Val-Tyr-Ile-His-Pro-Phe-OH.3CH₃COOH.4H₂O

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)